In my opinion, the fact that there are significant conflicts of interest that should have been disclosed is undeniable. Moreover, it is undeniable that these conflicts are relevant to the subject matter of the paper. The article makes the bold and I believe incorrect statement that treatment with drugs is the "standard of care" for smoking cessation. In fact, I believe that there are many methods that physicians appropriate use to promote smoking cessation in their patients, and medication is only one of these methods. Many physicians recommend other approaches, including counseling, hyponosis, 12-step programs, and cold turkey quitting.
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Because ANR is falsely accusing Mistic of being part of Big Tobacco, I am afraid that ANR is making a potentially defamatory statement. The false accusation appears to be malicious, as it ties Mistic to the historical fraud and conspiracy for which the tobacco companies were found guilty in the Department of Justice lawsuit. The accusation also appears to represent a blatant disregard for the truth, since there is absolutely no reason to even think that Mistic is owned by Big Tobacco, and because ANR does not list Mistic in its list of e-cigarette brands that are owned by tobacco companies. Thus, it appears that ANR is aware that Mistic is just an independent e-cigarette company."