Dr. Benowitz: "Dr. Benowitz, as a paid consultant for pharmaceutical companies, has assisted them with the design, development, and marketing of smoking-cessation products. Among the companies for which he has consulted on such products are GlaxoSmithKline plc and its affiliates (collectively, “GSK”); Pfizer, Inc. and its affiliates (collectively, “Pfizer”); Novartis AG and its affiliates (collectively, “Novartis”); Sanofi-Aventis U.S. LLC and its affiliates (collectively, “Sanofi-Aventis”); and Aradigm Corp. and its affiliates (collectively, “Aradigm”). During the last ten years, he has received at least approximately $10,000 per year for such consulting. He has also received grant support for research and writing from GSK and/or Pfizer on at least five occasions. In 2010, he co-authored a study, funded by Pfizer, on the use of its drug, Chantix, for smoking cessation."

Furthermore, it is well known that electronic cigarette users do not inhale more deeply than smokers. While smoke does enter the distal airways - which is why adenocarcinoma rates have increased so dramatically - vaping involves aerosol inhalation and the aerosol is mostly absorbed in the upper, not the lower airways. As with a nicotine inhaler, most of the nicotine absorption occurs in the upper airways.

With the release of its deeming regulations, the FDA is poised to give a huge gift to combustible tobacco and to the diseases and death caused by cigarettes. If promulgated as is, the regulations will be devastating to the public's health by protecting the combustible cigarette market at the expense of the introduction and promotion of much safer alternative products that would otherwise have the potential to substantially reduce lung disease, heart disease, stroke, and cancer.

Luchtenborg et al. that while non-filtered cigarettes increased the risk for colon cancer (OR 1.59; 95% CI, 1.15-2.21; P(trend) = 0.001), filtered cigarettes did not increase colon cancer risk (OR 1.05; 95% CI, 0.79-1.39; P(trend) = 0.98).

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