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By Stan's logic, we should throw out all the clinical trials upon which the established effectiveness of NRT is based because every one of these trials was designed to assess the efficacy of NRT among smokers who used these drugs with the specific intent to quit. Instead, according to Glantz's logic, we should examine the rate of smoking cessation among everyone who has ever used an NRT product. Doing that would lead to the conclusion that NRT is completely ineffective for smoking cessation.

The rest of the story is that the study actually did not find that 11.9% of the former smokers were addicted to nicotine at follow-up. Nor did it find that 2.9% of the baseline nonsmokers were currently addicted to nicotine.

Unfortunately, it does not appear that these investigators are truly interested in whether e-cigarettes help many smokers quit or not. Instead, I believe that these researchers have a pre-determined conclusion that e-cigarettes are ineffective and that they are trying to manufacture results that support their pre-determined conclusion.

Disclosure: I have not received any funding or compensation from the tobacco, electronic cigarette, or pharmaceutical industries. However, I am seeking funding from several electronic cigarette companies to conduct a behavioral study on the effects of electronic cigarettes on smoking behavior.

This lack of transparency in the report is unfortunate because readers deserve to be informed about financial conflicts of interest that could potentially have influenced the report's presentation and interpretation of the scientific evidence. This is especially important because the report makes broad conclusions regarding national strategies for smoking cessation. Thus, if the report's authors have received money from pharmaceutical companies that make the very products about which the report is opining, it would be critical to disclose these conflicts. The report fails to do so.


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