In one of the first studies to examine the trajectory of electronic cigarette use over time, Lechner and colleagues have shown that extended duration of electronic cigarette use is associated with

Instead, the law created a huge bureaucracy full of red tape and sluggish approval processes such that there are still close to 3500 substantial equivalence applications stacked up in a pile somewhere, and the FDA is so overburdened that it cannot even issue electronic cigarette regulations in a reasonable amount of time.

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