Yesterday, I explained that the of electronic cigarettes by Stan Glantz and colleagues published this week in the journal Circulation is because it draws conclusions about the efficacy of e-cigarettes for smoking cessation from studies that were not designed to measure such effects in the first place. These studies did not examine smoking cessation rates among a cohort of smokers who were identified at baseline as using e-cigarettes with the intention of quitting smoking. Moreover, smokers who use e-cigarettes are likely more heavily addicted to nicotine and may be more resistant to quitting, thus making inferences about cessation effectiveness from these studies inappropriate.

The inferiority of drugs to abrupt cold turkey quitting is not the only thing that the massive Surgeon General's report is hiding.

(See: Zhu S-H, et al. Four hundred sixty brands of e-cigarettes and counting: implications for product regulation. Tobacco Control. Published online ahead of print on June 17, 2014.)

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