According to CDC Director Dr. Thomas Frieden, the thousands of smokers who have quit smoking via electronic cigarettes are nothing but anecdotes. As Dr. Frieden told the Los Angeles Times in , referring to smokers who have quit using e-cigarettes: "the plural of anecdote is not data."

The authors acknowledge this: "We must state though that while the differences within our study are of statistical significance, the clinical changes may be too small to be of major clinical importance."

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