According to the of the grant proposal, the research question that the lab team is proposing to investigate is as follows: "The goal of this application is to determine the effects of Third Hand Smoke on wound healing. ... It is known that first-hand smoke and secondhand smoke (SHS) inhibit wound healing but nothing is known about the effects of third-hand smoke (THS) on wound healing. ... To address this problem, we will use mice, expose them for 6 months to THS present in their cages and, at the end of the exposure period, we will perform wounds on their backs and study the time course of healing by examining not only the wound areas but also the properties of the tissues."

Smoking status was then assessed at the time of the interview to determine the rates of successful quitting during the most recent quit attempt, comparing the three groups: (1) e-cigarettes only; (2) NRT only; and (3) no cessation aids. The total sample size was 5,863.

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