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2. The subjects did not provide informed consent for their participation in the research.

"Thanks again for making time to see us, this is an area of much focus globally and we are committed to bringing these products to market and so reducing the harm caused by smoking in the population," the letter said.

There is no justification for drawing this sweeping conclusion based solely on studies of mouse brains, without a shred of clinical or epidemiologic evidence that suggests e-cigarettes serve as a gateway to smoking or illicit drug addiction. And I think it is inappropriate to engage in this kind of scaremongering.

1. The use of electronic cigarettes has increased dramatically, ever since the fourth quarter of 2011.

As the authors point out: "Of interest, consistent improvements in subjective and objective asthma outcomes were also observed amongst dual users (i.e., heavy reducers) with no real difference in dual compared to single users by the end of the observation period."


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