This seemed surprising at first as the current trend shows the high the PG level the more of the three chemicals that will be released. However a reasonable explanation would be the flavoring used in the 50/50 ratio E-Juice. E-Juice flavorings (especially the low quality type) can be alcohol based thus the increase of acetone being released. Capella and The FlavorApprenticeare two companies that avoid acetone in their flavoring solutions. Sonot all E-Juice have to have acetone.

Unquestionably, there is still the need to regulate the sale and marketing of electronic cigarettes to minors. Sadly, and ironically, the only ones who seem to oppose laws to ban the sale of e-cigarettes to minors are the supposedly "anti-smoking" groups.

Neither the survey approach or the RCT approach is perfect. Both have major strengths and significant limitations. The best way to proceed is to conduct both types of studies and to synthesize the results across study designs, keeping in mind the methodological strengths and limitations of each individual study. Only by looking at this totality of the evidence can we draw valid scientific conclusions.

The article

This is the equivalent of a cigarette company refuting the required warnings that are made on a cigarette package. The cigarette companies are free to fight the cigarette warning labels as they are being considered, but once a federal body requires those warnings, the companies must not act to undermine the required warnings. In this case, Pfizer's actions are more grievous than those of a cigarette company undermining a package warning because the black box warnings are required by a federal regulatory safety agency, rather than by a Congressional act. More specifically, the black box warnings are an official part of the formal approval of the marketing and sale of the drug. The company may not sell the drug without the warning. By publicly undermining and refuting the warning, the company is essentially violating the terms of the drug's approval.

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