In fact, I went so far as to the of four FDA Tobacco Products Scientific Advisory Committee (TPSAC) panel members - Dr. Neal Benowitz, Dr. Jack Henningfield, Dr. Dorothy Hatsukami, and Dr. Jonathan Samet - because they had significant conflicts of interest with pharmaceutical companies that made it impossible for them to offer objective advice to the Agency on federal tobacco regulatory policy matters.

A recent from the UK involved a survey of 12,171 adults in February and March of this year. The survey found that 4.7% of ex-smokers were regularly using electronic cigarettes. Among these ex-smokers, 71% reported that they were using e-cigarettes to try to quit smoking and 48% reported that they were using e-cigarettes to try to keep off tobacco products. These data suggest that the overwhelming majority of ex-smokers using e-cigarettes are people who smoked and then quit smoking because of these products, rather than ex-smokers who returned to nicotine use via e-cigarettes.

The rest of the story is that despite the Common Rule and the intense efforts to try to prevent human subject violations in research, there are still occasional studies which find their way through the cracks. This is one bad example. It is an example of an unethical experiment that should never have been approved by an IRB in its current form because it blatantly violates the ethical principles of both consent and informed consent.

The Surgeon General's concludes that: "The introduction of ventilated filters, or changes in the design and composition of cigarettes that accompanied their introduction, may have increased the carcinogenicity of cigarette smoke."

"Thanks again for making time to see us, this is an area of much focus globally and we are committed to bringing these products to market and so reducing the harm caused by smoking in the population," the letter said.

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