If a product submits an application for a new product approval or substantial equivalence determination within the allotted 24-month period, it will not be taken off the market while the review of the application is pending.

It is clear, then, that this study violated the principles of informed consent, as subjects did not provide informed consent prior to being enrolled in the research.

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• There is no evidence at the current time that kids are starting out with e-cigarettes and then going on to smoke conventional cigarettes.

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