Yesterday, I explained that the of electronic cigarettes by Stan Glantz and colleagues published this week in the journal Circulation is because it draws conclusions about the efficacy of e-cigarettes for smoking cessation from studies that were not designed to measure such effects in the first place. These studies did not examine smoking cessation rates among a cohort of smokers who were identified at baseline as using e-cigarettes with the intention of quitting smoking. Moreover, smokers who use e-cigarettes are likely more heavily addicted to nicotine and may be more resistant to quitting, thus making inferences about cessation effectiveness from these studies inappropriate.

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