The problem with e-cigarette experimentation, for the prospects of cigarette smoking initiation, is that youth are getting used to sweet and flavored products. It is going to be extremely difficult to go from the sweet and flavored taste of the electronic cigarette to the harsh taste of a tobacco cigarette. That transition is not favored, at least not on a theoretical basis. Why would a youth switch from a cherry e-cigarette to a Marlboro?

Yes, this is satire. But it makes the point that the very same arguments that the lawmakers are using to implicate electronic cigarettes in targeting youth could be made to implicate nicotine replacement products such as nicotine gum and lozenges.

Some of the most important conclusions in epidemiologic research have come not from large case-control or cohort studies or clinical trials, but from case studies or case series, or as Dr. Frieden would say, "anecdotes."

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