The bottom line: it appears that the use of electronic cigarettes has tremendous health benefits not only for those who quit smoking, but also for those who become dual users. While it may take longer for these individuals to eventually get off of nicotine altogether, it appears that the switch to e-cigarettes yields a much lower level of nicotine addiction, making it easier, not harder, to subsequently cease using nicotine if they so desire.

For years, we in tobacco control have attacked tobacco industry-funded scientists or researchers who consulted for tobacco companies for not disclosing their conflicts of interest. It it therefore quite unfortunate, and ironic, that tobacco control researchers do not appear to take their own conflicts of interest seriously and that they, too, are hiding these conflicts from the public.

In my opinion, it is the responsibility of the company that markets the drug in question not to undermine, refute, or publicly challenge the black box warning once the FDA has made a decision to require this warning. It is the FDA's scientific judgment, not that of the pharmaceutical company, that should be the final word in making the decision about whether or not a black box warning is required and what the black box warning should state. If the company refutes the black box warning publicly once it has been required, then it is essentially thumbing its nose at the FDA and substituting its own scientific judgment for that of the agency.

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