Trueba et al. also found that higher depressive mood was associated with greater reductions in exhaled nitric oxide.

Some further speculation on why I did not feel that jolt of energy throughout the day is due to the fact infusing caffeine with E-Juice can’t be done without destroying the taste of E-Juice. A cup of coffee is roughly 100mg of caffeine. To get the same effects as a single cup of coffee, the E-Juice mixologist would have to mix a very high concentration of caffeine in each bottle of E-Juice. No one is going to use an entire of bottle of E-Juice in one sitting, so 100mg of caffeine would have to be ingested in just a few short puffs for the user to feel the effects without chain vaping.

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