These data all but destroy the gateway hypothesis. They demonstrate that at the current time, the evidence simply does not support the assertion that the proliferation of e-cigarette use among youth is leading to increased smoking initiation. Electronic cigarettes are not leading to a lifetime addiction to cigarette smoking among our nation's youth.

One of the first things you need to decide is if you like a sweeter taste, or a real tobacco taste. At first, many smokers prefer an e-juice with a tobacco taste, but many will gradually shift into sweeter flavors like apple or strawberry.

1. That there is a causal link between traditional smokeless tobacco use and oral cancer; and

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