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"In summary, the rules state:

While it is theoretically possible that an electronic cigarette company could some day get a full reduced risk claim approved, the regulatory burden is extreme. Not only would the company have to show that the product is safer than smoking, but the company would also have to demonstrate that the product will not deter smokers from quitting and will not introduce youth to the use of nicotine. The studies required would be substantial. For most companies, the costs would be prohibitive. It would take many years before any company could even have a reasonable chance of getting such an application approved and by then it will be too late for the market to continue to expand.

At this point, I decided to add a heat source so the flavoring can bond with the base. Originally I thought about putting it in the microwave, but that didn’t seem like a good idea as the bottle was so small. Instead, I filled a tall glass with hot water and put my bottle of E-Juice in until the water cooled off. I repeated this process about three times before the liquid in my bottle stopped being cloudy and became clear. I let it cooldown a bit and tried it out. I wasn’t impressed at all with my hard work and labor. The E-Juice was quite bland with how I made it, but it was my first try and I’ve learned quite a bit since then.

Perhaps the most useful contribution of this paper is that it readily demonstrates why the approach being used by Stan Glantz to assess the effectiveness of e-cigarettes for smoking cessation is inappropriate and leads to erroneous conclusions.


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