The problem with e-cigarette experimentation, for the prospects of cigarette smoking initiation, is that youth are getting used to sweet and flavored products. It is going to be extremely difficult to go from the sweet and flavored taste of the electronic cigarette to the harsh taste of a tobacco cigarette. That transition is not favored, at least not on a theoretical basis. Why would a youth switch from a cherry e-cigarette to a Marlboro?

I believe that such a modified, randomized clinical study is essential to add another line of evidence with which to evaluate the potential benefits of electronic cigarettes. Yes, there are limitations to RCTs, but it makes no sense to throw out the baby with the bath water.

5. Quality control for stated nicotine levels; and

The misinformation in the tobacco control field is so widespread that hardly a day goes by that an anti-smoking advocate somewhere doesn't publicly declare that smoking may be no more dangerous than vaping. Yesterday, it was the Sedgwick County Health Department (Wichita, KS), which wrote in an op-ed in the Kansas City Star:

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