Suppose that there are 1000 e-cigarette users who enter the cancer center with a diagnosis of cancer. Of these, an amazing 900 were able to quit smoking. However, 100 were very resistant smokers and could not quit smoking, even with e-cigarettes. Note that it would be these 100 resistant smokers who would be enrolled in the study. The 900 ex-smokers who quit using e-cigarettes would not be eligible for the study, because they no longer smoke.

And that, more than anything else, is what scares me about the FDA's approach to the regulation of cigarettes and electronic cigarettes.

First, disclosure of conflicts of interest has become a widely accepted guideline for ethical practice in medicine and public health. Most, if not all, reputable public health and medical journals require authors to disclose any relevant conflicts of interest and most journals publish any conflicts that are disclosed.

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