"There is no evidence, no convincing evidence that using e-cigarettes leads to people quitting, there's not even convincing evidence it leads to people smoking less, although that might be possible," he said.

The study enrolled 1,074 patients with cancer who were smokers and were therefore referred to a tobacco treatment program at a comprehensive cancer center during the years 2012 and 2013. Smoking status, nicotine dependence, and e-cigarette use was assessed at baseline and the patients were followed for six-month. The primary outcome was smoking cessation, measured as seven-day abstinence at follow-up.

In 2014, the tobacco companies have changed their behavior and have ceased and desisted from arguing that even major differences between cigarette brands render them different in terms of overall public health risk. In fact, Philip Morris has explicitly the following: "As of today ... there is no cigarette on the market that public health organizations endorse as offering 'reduced risk.' If smokers are concerned about the risks of cigarette smoking, the best thing to do is quit."

In my opinion, Dr. Glantz's conclusion from this study is unscientific, illogical, and extremely damaging and destructive to the FDA's consideration of this issue as well as to the public's appreciation of the severe hazards of cigarette smoking.

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