Per rumor only, I am expecting the FDA electronic cigarette deeming regulations to be released today. It will take me some time to digest and analyze them, but as soon as I do, I will provide a summary and commentary on their implications.

Harris et al., in perhaps the most comprehensive and definitive on this issue, found a clear increase in cancer risk associated with non-filtered cigarettes. As they reported: "Compared with smokers of medium tar (15-21 mg) filter cigarettes, risk was higher among men and women who smoked high tar (> or = 22 mg) non-filter brands (hazard ratio 1.44, 95% confidence interval 1.20 to 1.73, and 1.64, 1.26 to 2.15, respectively)."

There is strong evidence that electronic cigarettes are much safer than tobacco cigarettes. These products contain no tobacco and do not involve combustion. Multiple studies have confirmed that there are only a few chemicals present beyond the nicotine, and so far, only trace or low levels of potentially concerning constituents have been detected - levels which are much lower than in real cigarettes. Users of these products generally report an immediate and dramatic reduction in respiratory symptoms. Moreover, there is strong evidence that electronic cigarettes can be effective in smoking cessation and that they may actually be more effective than traditional nicotine replacement products such as nicotine patches, gum, or lozenges. Even when not effective in promoting complete smoking cessation, these products generally help smokers cut down substantially on the amount they smoke, thus sharply curtailing tobacco cigarette sales.

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