In fact, in a by Flouris et al., the investigators found that real cigarettes, but not the fake ones, had a significant detrimental effect on pulmonary function, measured by spirometry. This study documents that while active smoking has immediate, clinically meaningful effects in reducing lung function, electronic cigarettes do not.

Frankly, as I predicted prior to the enactment of the Family Smoking Prevention and Tobacco Control Act, the FDA's regulation of tobacco products is a national public health embarrassment.

For example:

Although it seems like a fantastic idea, the idea of having caffeine in your E-Juice is most likely a gimmick. Considering caffeine naturally has a very bitter taste, dissipates at high heat, and only 60% potent when inhaled caffeine infused E-Juice doesn’t seem to be a viable option. Unless you’re okay with super concentrated caffeine that tastes very bitter, you’re better off getting your morning fix from coffee rather than looking at E-Juice as an alternative.

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