There is a part of this story that was not revealed at the hearing, and it is time to reveal it now at the Rest of the Story.

By publicly refuting the black box warning, Pfizer is literally spitting in the face of the FDA. This is not appropriate. The company should either be penalized and forced to discontinue its campaign of refutation of the black box warning findings, or the drug should be pulled from the market due to a finding that the company has violated the terms of the drug's approval.

One thing that is true is that there are no cardiovascular benefits to smoking reduction. The reason for this is that the adverse cardiovascular effects of smoking saturate at a low level of exposure. However, with carcinogenic effects as well as lung disease, there is a well-recognized dose-response relationship between exposure and disease risk. Therefore, substantial smoking reduction has no cardiovascular benefit but it does lower lung cancer risk and respiratory morbidity.

These studies are simply ignored by the Surgeon General's report and by my colleagues who have attacked me. It would be one thing if there were no evidence for my opinions, but it's hardly appropriate to attack an individual for expressing an opinion that is backed up by scientific studies.

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