According to the of the grant proposal, the research question that the lab team is proposing to investigate is as follows: "The goal of this application is to determine the effects of Third Hand Smoke on wound healing. ... It is known that first-hand smoke and secondhand smoke (SHS) inhibit wound healing but nothing is known about the effects of third-hand smoke (THS) on wound healing. ... To address this problem, we will use mice, expose them for 6 months to THS present in their cages and, at the end of the exposure period, we will perform wounds on their backs and study the time course of healing by examining not only the wound areas but also the properties of the tissues."

As tobacco control advocates commemorate the 50th anniversary of the release of the 1964 Surgeon General's report on smoking by Dr. Luther Terry, we are praising Dr. Terry for his groundbreaking and pivotal work that many view as having started the tobacco control movement. Dr. Terry served as Surgeon General of the United States Public Health Service from 1961 to 1965.

For this reason, I am discouraged about the possibility that people like Dr. Glantz and Dr. Chapman will change their minds about the potential utility of e-cigarettes if further evidence accumulates to demonstrate the benefits of these products. The science is simply not going to matter to them. Hopefully, the science will matter to the FDA.

This argument might have some plausibility if electronic cigarettes were "starter cigarettes." In other words, if electronic cigarettes were much milder versions of tobacco cigarettes, with milder tobacco flavor, then it might be expected that youth could advance from an electronic cigarette to a real one. Electronic cigarettes with tobacco or menthol flavoring, for example, might be expected to get kids used to the taste of a tobacco cigarette and thus to promote cigarette smoking initiation.

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