The impression I am left with is that the entire harm reduction debate is a toxic one, with venom on both sides, which is leading to irrational thinking, blind adherence to ideology, a focus on ad hominem attacks rather than rational scientific discourse, and a biased perspective on the scientific evidence.

For example, one of the major problems in some of the previous survey studies of electronic cigarettes (the ones cited by Stan Glantz, for example) is that they fail to control for a major confounder: the level of a smoker's addiction to smoking and motivation to quit. Some of the studies that Glantz has cited to show that e-cigarettes are ineffective for smoking cessation compare users of e-cigarettes and non-users of e-cigarettes. In two of these studies, those who did not use e-cigarettes had higher quit rates.

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