The Rest of the Story

Since nothing is known about the effects of third-hand smoke on wound healing, it seems very appropriate that this research team is going to investigate this research question using a mouse model to find out whether there are adverse effects of thirdhand smoke.

One thing that is true is that there are no cardiovascular benefits to smoking reduction. The reason for this is that the adverse cardiovascular effects of smoking saturate at a low level of exposure. However, with carcinogenic effects as well as lung disease, there is a well-recognized dose-response relationship between exposure and disease risk. Therefore, substantial smoking reduction has no cardiovascular benefit but it does lower lung cancer risk and respiratory morbidity.

These data add to the increasing evidence that the dramatic increases in youth experimentation with electronic cigarettes are not leading to increased smoking. The gateway hypothesis - that e-cigarette use leads to smoking - does not appear to be supported by any evidence at the current time.

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