In fact, this is precisely what Trueba et al. demonstrated in a of changes in exhaled nitric oxide levels in 41 healthy college students.

Perhaps the most useful contribution of this paper is that it readily demonstrates why the approach being used by Stan Glantz to assess the effectiveness of e-cigarettes for smoking cessation is inappropriate and leads to erroneous conclusions.

Included in a recent editorial, Dr. Michael Katz mentioned that the FDA should monitor electronic cigarettes as a nicotine delivery tool, and that electronic cigarettes should continue to be banned in locations where typical tobacco products are not allowed. “Unfortunately, the evidence on whether e-cigarettes help smokers to quit is contradictory and inconclusive,” Katz wrote. He did say he was willing to support their use if “there were good data indicating that they helped smokers to stop.” Dr. Gilbert Ross, medical and executive director of The American Council on Science and Health, said “allowing e-cigs to compete with cigarettes in the marketplace might decrease smoking-related morbidity and mortality.”

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