Readers should be cautioned that this study should not be used to conclude that e-cigarettes are twice as effective as NRT for smoking cessation generally, for reasons explained articulately by Carl Phillips in his on this study.

What would be an example of such a severe problem that it warrants reporting to the FDA? to the medical branch chief in the Office of Science at FDA's Center for Tobacco Products, such a severe problem would be something like if a cigarette "just smells or tastes wrong."

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