As I found out when I simply proposed the rather benign, but crucial to science, idea of conducting a clinical trial to examine the effects of electronic cigarettes on smoking behavior (in comparison to the nicotine patch, a well-accepted standard), there is very little room for balanced, objective thinking in the current tobacco control/harm reduction environment. The simple proposal to conduct such a crucial study brought out personal attacks and profound criticism. This despite the fact that every single electronic cigarette company representative I talked to about the proposal felt that the study was critical and needs to be conducted. There was no opposition to conducting sound science among the electronic cigarette companies. All the opposition came from the harm reduction "community."

1. The subjects did not consent to participate in the study.

At the time the experiment was initiated in 1932, the treatment for syphilis involved toxic drugs. However, by the 1940's, penicillin was readily available as a treatment for this infection. Nevertheless, the study continued and penicillin was not made available to these black men. Nor were they informed about the availability of the medicine or even of what disease they actually had.

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