Long-term, there is a significant reduction in lung cancer risk associated with cutting the amount one smokes. The study that Glantz cites as showing no health benefits of smoking reduction actually found a associated with smoking reduction.

What a great public health accomplishment it was to put cigarettes under the jurisdiction of the Food and Drug Administration. Although the FDA has so far done not a single thing to address cigarette safety problems such as heart disease, lung disease, and cancer, we can all breathe easier knowing that the FDA will plunge into action if a smoker somewhere reports that a cigarette doesn't smell or taste right.

It is easy to see why this methodology is inappropriate to assess smoking cessation rates among smokers who use e-cigarettes in an attempt to quit smoking.

"All patients being treated with CHANTIX should be observed for neuropsychiatric symptoms including changes in behavior, hostility, agitation, depressed mood, and suicide-related events, including ideation, behavior, and attempted suicide. These symptoms, as well as worsening of pre-existing psychiatric illness and completed suicide, have been reported in some patients attempting to quit smoking while taking CHANTIX in the postmarketing experience. ... Advise patients and caregivers that the patient should stop taking CHANTIX and contact a healthcare provider immediately if agitation, hostility, depressed mood, or changes in behavior or thinking that are not typical for the patient are observed, or if the patient develops suicidal ideation or suicidal behavior."

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