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The study enrolled 1,074 patients with cancer who were smokers and were therefore referred to a tobacco treatment program at a comprehensive cancer center during the years 2012 and 2013. Smoking status, nicotine dependence, and e-cigarette use was assessed at baseline and the patients were followed for six-month. The primary outcome was smoking cessation, measured as seven-day abstinence at follow-up.

Long-term, there is a significant reduction in lung cancer risk associated with cutting the amount one smokes. The study that Glantz cites as showing no health benefits of smoking reduction actually found a associated with smoking reduction.

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