Some of the researchers and advocates who opposed our crowdfunding campaign to raise money for a randomized behavioral study of the effects of electronic cigarettes on smoking behavior argued that randomized clinical trials (RCTs) are simply not appropriate to study e-cigarettes because they cannot simulate the real-life situation, where smokers have many choices of different types of products, can engage with social networks, and can experiment over time, change products, advance from one type of product to another, etc.

Prior to this study, the most significant health concern regarding passive vaping was the possibility of exposure to carcinogenic and toxic aldehydes and pyrolysis products including formaldehyde, acrolein, and acetone. However, this study found no increase in concentrations of any of these pollutants under realistic (real-life) conditions.

Yesterday, I that the 2014 Surgeon General's , released last Friday, failed to disclose the financial conflicts of interest of many of its authors. Specifically, the report is hiding the fact that many of its authors have or had financial conflicts of interest with pharmaceutical companies that manufacture the smoking cessation products about which the report provides a misleadingly positive review.

Unfortunately, the 2014 Surgeon General's report has left readers unaware of possible industry influences, as it has failed to disclose the pharmaceutical industry ties of many of its authors. And it is not difficult to estimate the extent to which pharmaceutical industry-generated research activities have influenced scientific thinking regarding the effects of smoking cessation drugs and nicotine's therapeutic (cessation) applications.

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