That sounds like something the tobacco industry would say if asked to comment about electronic cigarettes. And to its credit, even the tobacco industry has not made any such statement.

At the end of the day, while there are some positive aspects to these regulations, it is clear that science is not playing much of a role in the process. That does not bode well for the potential of electronic cigarettes to seriously challenge the combustible tobacco market, and thus to save hundreds of thousands of lives.

Falk et al., in a of the risk for laryngeal cancer, found that: "Higher risks were associated with smoking nonfiltered than filtered cigarettes." For those who smoked filtered cigarettes, the OR was 5.9 (95% CI = 2.4-14.4); for those who smoked non-filtered cigarettes, the OR was 9.0 (95% CI = 3.2-25.1).

A third major advantage of a clinical trial is that conditions are controlled as carefully as possible, minimizing potential biases. Both sampling and measurement bias are greatly reduced, if not eliminated. In contrast, survey studies are generally subject to significant sampling and measurement bias.

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