Even if e-cigarette vapor shows some toxicity in cell culture studies, how does that demonstrate that vaping is more harmful than smoking?

These results, while preliminary, provide initial evidence that electronic cigarettes may serve not only as a means of helping smokers to quit, but also of helping them to eventually become free of nicotine addiction.

What the study did show was subclinical evidence of impaired lung function, meaning that the observed (measurable) lung function was unchanged, but that there was evidence of physiologic effects consistent with some bronchial inflammation. What is not known is whether this acute bronchial inflammation has any significance in the long-term. The presence of bronchial inflammation may be a result of propylene glycol having a respiratory irritant effect. But this does not necessarily mean that long-term exposure would lead to any adverse effect on lung function. More research is necessary to clarify that point.

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