Unfortunately, the 2014 Surgeon General's report has left readers unaware of possible industry influences, as it has failed to disclose the pharmaceutical industry ties of many of its authors. And it is not difficult to estimate the extent to which pharmaceutical industry-generated research activities have influenced scientific thinking regarding the effects of smoking cessation drugs and nicotine's therapeutic (cessation) applications.

The study concludes that "e-cigarette use is aggravating rather than ameliorating the tobacco epidemic among youths."

"It is difficult to estimate the extent to which industry-generated research activities have influenced scientific thinking regarding the effects of nicotine on cognitive performance and on nicotine’s therapeutic applications. Authors’ industry affiliations and potential conflicts of interest reported in publications may go unnoticed by readers, may be difficult to identify, or may not be disclosed at all. Reviews and other articles citing industry-affiliated studies generally did not include author affiliations or potential conflicts of interest at all, leaving the readers unaware of possible industry influences."

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