The full effect of using electronic cigarettes on people’s health has yet to be established as e-cigs are a relatively new device and long term effect studies simply do not yet exist. Though there is only limited research at this time, the studies that do exist primarily seem to agree that the electronic method of delivering tobacco to your system is significantly safer than the traditional method of combustible smoking, which exposes the user to noxious smoke and tar. The AHA policy statement read: “To date, relatively little research has been conducted on the human health effects of e-cigarettes.” They go on to cite a study by the American Journal of Preventative Medicine, in which they found that, “no serious adverse effects have been reported in clinical trials with less than 6 months of use compared with nicotine patches.” Users who are trying to quit smoking and using nicotine replacement often report having more success with e-cigarettes as a cessation method for a variety of reasons. Not only do vapor cigarettes deliver the nicotine in a safer way, they also allow the user to have an enjoyable experience, one that is similar to traditional smoking, which many smokers agree is often just as much of a part of their addiction as the nicotine itself.

By publicly refuting the black box warning, Pfizer is literally spitting in the face of the FDA. This is not appropriate. The company should either be penalized and forced to discontinue its campaign of refutation of the black box warning findings, or the drug should be pulled from the market due to a finding that the company has violated the terms of the drug's approval.

Jacob Sullum provides an of the literature on this topic, pointing out that there is very strong data to demonstrate that the flavors are what attract many smokers to try to quit using electronic cigarettes. You have to read his whole column, but to summarize:

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