Because products are substantially equivalent only if they pose no different issues of public health, and because flavorings can affect product efficacy and safety, it is probable that every different flavor of every different brand must submit a separate application. Thus, at a minimum, there are going to be at least 466 x 49 applications, or 22,834 required applications.

Furthermore, the Lung Association's position is not at all science-based. There is no evidence that electronic cigarettes are contributing to "more disease, death, and misery." In fact, the current evidence suggests that electronic cigarettes are contributing significantly to the reduction of disease, death, and misery.

First and foremost regular cigarettes produces many carcinogens, , including formaldehyde, acetaldehyde, and acetone. These three chemicals were tested in the study to see what levels are released when electronic cigarettes are used. The study E-Juice that was purchased at the store (not a custom blend) and was a 50PG/50VG ratio. 100% VG and 100% PG was used as the control groups.

"By improving symptoms of depression, smoking may actually enhance respiratory health."

The degree to which electronic cigarettes stimulate or depress overall interest in quitting is a separate and empirically answerable question. In fact, evidence from the UK indicates that the spread of electronic cigarettes has been associated with a in the desire to quit smoking at a population level.

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