Some of the researchers and advocates who opposed our crowdfunding campaign to raise money for a randomized behavioral study of the effects of electronic cigarettes on smoking behavior argued that randomized clinical trials (RCTs) are simply not appropriate to study e-cigarettes because they cannot simulate the real-life situation, where smokers have many choices of different types of products, can engage with social networks, and can experiment over time, change products, advance from one type of product to another, etc.

Another problem with what Dr. Glantz has done is that it is fundamentally dishonest. He is essentially lying to the public about the science regarding electronic cigarettes. He knows full well - as he acknowledges in the paper - that this study provides no answer regarding whether e-cigarettes precede and lead to smoking or whether youths who are heavier and more dependent smokers are more likely to experiment with e-cigarettes. Nevertheless, he is telling the public that he has answered the question and that the answer is that e-cigarette use precedes and leads to smoking. This is tantamount to lying to the public.

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