As I found out when I simply proposed the rather benign, but crucial to science, idea of conducting a clinical trial to examine the effects of electronic cigarettes on smoking behavior (in comparison to the nicotine patch, a well-accepted standard), there is very little room for balanced, objective thinking in the current tobacco control/harm reduction environment. The simple proposal to conduct such a crucial study brought out personal attacks and profound criticism. This despite the fact that every single electronic cigarette company representative I talked to about the proposal felt that the study was critical and needs to be conducted. There was no opposition to conducting sound science among the electronic cigarette companies. All the opposition came from the harm reduction "community."

Instead, I think that studies which specifically compare lung cancer risk between lifelong smokers of filtered vs. non-filtered cigarettes during the same time period are most informative regarding the relative cancer risks of these products. And multiple studies along these lines, including recent studies, have reported a slightly decreased risk associated with lifetime smoking of filtered vs. non-filtered cigarettes.

"It is anticipated that Nicoventures will be making a formal application to the TGA in the near future.

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