The authors admit this in the paper. They write: "This is a cross-sectional study, which only allows us to identify associations, not causal relationships."

The requirement by the FDA that this black box warning be placed on Chantix is based on the agency's assessment of hundreds of cases of suicides that occurred in patients who had recently been treated with the drug, as well as thousands of cases of other serious adverse neuropsychiatric symptoms associated with the use of Chantix. In making a decision to require a black box warning, the agency takes into consideration the likelihood that the observed association between the drug and the adverse effects is a causal one.

According to the letter: "Today Rep. Henry A. Waxman, Sen. Tom Harkin, and Rep. Peter Welch sent a letter to California Attorney General Kamala D. Harris, Iowa Attorney General Tom Miller, and Vermont Attorney General William H. Sorrell urging them to classify electronic cigarettes as cigarettes under the Tobacco Master Settlement Agreement (MSA) to prevent e-cigarette companies from targeting youth and getting them addicted to their products. ... Classifying e-cigarettes as cigarettes under the MSA would prohibit tobacco companies from targeting youth in advertising and marketing of these products."

The Rest of the Story

A good amount of us are ex-smokers that picked up an E-Cig and have never turned back. We switch for many reasons and we’re all well aware of the dangers of regular tobacco cigarettes and even its second hand smoke. But what about the vapor we are inhaling and the vapor being exhaled. There has been much controversy on the matter as there just isn’t much research being done on it.

I was awed by the efficiency of his E-Juice making setup. I bluntly asked him about his investment in such a machine and he just told me that the store has gotten so busy that he could not meet the demands of his customers unless he either hired 10 more people just to bottle his E-Juice or he invested in the machine. The way he saw it with almost a dozen people handling nicotine ratios and flavoring there was bound to be human error at least a few times a day and he wanted to avoid that at any cost as he understood the dangers of nicotine poisoning. It seemed like a perfect setup and a well-oiled machine he was running in his shop.

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