2. Lorillard: "FDA should exercise enforcement discretion not to require premarket review of electronic cigarettes introduced into United States commerce on or before the effective date of the final deeming regulation.

Thus, the authors readily acknowledge that it is impossible from this study to determine whether or not e-cigarettes lead to smoking or whether smoking leads to e-cigarette experimentation.

As tobacco control advocates commemorate the 50th anniversary of the release of the 1964 Surgeon General's report on smoking by Dr. Luther Terry, we are praising Dr. Terry for his groundbreaking and pivotal work that many view as having started the tobacco control movement. Dr. Terry served as Surgeon General of the United States Public Health Service from 1961 to 1965.

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