Some of the researchers and advocates who opposed our crowdfunding campaign to raise money for a randomized behavioral study of the effects of electronic cigarettes on smoking behavior argued that randomized clinical trials (RCTs) are simply not appropriate to study e-cigarettes because they cannot simulate the real-life situation, where smokers have many choices of different types of products, can engage with social networks, and can experiment over time, change products, advance from one type of product to another, etc.

It shouldn't take a rocket toxicologist to figure out that electronic cigarettes - which contain no tobacco - have immense benefits over traditional tobacco products. It shouldn't take a rocket epidemiologist to figure out that eliminating almost all of the more than 10,000 chemicals and 60+ carcinogens in cigarettes is going to result in a safer product. And anyone who has read the numerous laboratory, toxicology, and clinical studies of electronic cigarettes and tobacco cigarettes should understand that vaping is much safer than smoking.

Per rumor only, I am expecting the FDA electronic cigarette deeming regulations to be released today. It will take me some time to digest and analyze them, but as soon as I do, I will provide a summary and commentary on their implications.

The commentaries by the two former tobacco industry consultants, university professors at a major midwestern medical school, are not in any way pro-tobacco, although they do criticize a number of current anti-smoking initiatives because they are ineffective and not based on sound formative research.

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